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  • 2019 Apr 03

    G HAMILTON (Emulate)

    6:30pm to 8:30pm

    Location: 

    48 Quincy St, Rm 112, Cambridge, MA 02138, USA
    Geraldine A. Hamilton is the President and Chief Scientific Officer of Emulate. Prior to joining Emulate’s founding team, she served as Lead Senior Staff Scientist with the Wyss Institute for Biologically Inspired Engineering at Harvard University. At the Wyss Institute, Hamilton lead the Organs-on-Chips program and managed the multidisciplinary team responsible for developing, translating and commercializing the Organs-on-Chips technology. Hamilton’s career spans industry, academia and the start-up world.
  • 2019 Apr 03

    T WHITE (Colorado)

    4:30pm to 5:30pm

    Location: 

    Pierce Hall, Rm 209, 29 Oxford St, Cambridge, MA 02138, USA
    Liquid crystalline materials are pervasive, enabling devices in our homes, purses, and pockets. It has been long-known that liquid crystallinity in polymers enables exceptional characteristics in high performance applications such as transparent armor or bulletproof vests. This talk will generally focus on a specific class of liquid crystalline polymeric materials: liquid crystalline elastomers. These materials were predicted by de Gennes to have exceptional promise as artificial muscles, owing to the unique assimilation of anisotropy and elasticity. Subsequent experimental studies have... Read more about T WHITE (Colorado)
  • 2019 Mar 29

    H LEVINE (Rice)

    4:00pm to 5:00pm

    Location: 

    Maxwell Dworkin G115
    "What is epithelial-mesenchymal plasticity, what does it have to do with physics, and why is it important for metastasis?" Until very recently most cancer biologists operated with the assumption that the most common route to metastasis involved cells of the primary tumor transforming to a motile single-cell phenotype via complete EMT (the epithelial-mesenchymal transition). This change allowed them to migrate individually to distant organs, eventually leading to clonal growths in other locations. But, a new more nuanced picture has been emerging, based on advanced measurements and on... Read more about H LEVINE (Rice)
  • 2019 Mar 29

    D GIFFORD (MIT)

    12:00pm to 1:00pm

    Location: 

    Sherman Fairchild, Rm 268, 7 Divinity Ave, Cambridge, MA 02138, USA
    “Machine Learning-Based Antibody Design & Neoantigen Discovery” Dr. Gifford is a Professor of Computer Science and Biological Engineering in the Departments of Electrical Engineering and Computer Science at Massachusetts Institute of Technology.
  • 2019 Mar 28

    QBS Seminar

    Repeats every week every Thursday until Wed Apr 03 2019 .
    5:00pm to 6:00pm

    Location: 

    Northwest Building, Rm 353, 52 Oxford St, Cambridge, MA 02138, USA
    QBS isn't another seminar. It's a place for collaboration and discussion. Speakers--alternating between faculty and students--give chalk talks and encourage questions throughout. You won't find any hour-long slide decks here, but you will find pizza, beer, and other quantitatively minded researchers from biology, physics, engineering, math, and more. Join us every Thursday evening at 5 pm to talk about interesting ideas... and maybe spark a few ideas of your own. To sign up for the QBS announcement listserv: https://lists.fas.harvard.edu/mailman/listinfo/qbs Read more about QBS Seminar
  • 2019 Mar 28

    QBS: Amanda Kedaigle & Silvia Velasco

    5:00pm to 6:00pm

    Location: 

    Northwest Building, Rm 353, 52 Oxford St, Cambridge, MA 02138, USA

    Amanda Kedaigle & Silvia Velasco
    (joint talk, Regev Lab & Arlotta Lab)

    When making a brain in a flask,
    It’s perfectly natural to ask:
    Will it look the same when
    I grow it again?
    Reproducible: that is our task.

    Stem cell-derived human brain organoids hold great promise for studying the development and function of the human brain and provide an invaluable tool to model neurological diseases. However, the utility of these model systems has been hampered by the limited characterization and comparison of the cell types and features produced... Read more about QBS: Amanda Kedaigle & Silvia Velasco
  • 2019 Mar 28

    C PEHLEVAN (Harvard)

    3:00pm to 4:00pm

    Location: 

    Pierce Hall, Rm 209, 29 Oxford St, Cambridge, MA 02138, USA
    "What Learning Objectives Does Hebbian Plasticity Optimize?" Synaptic plasticity is widely accepted to be the mechanism behind learning in the brain’s neural networks (NNs). A central question is how synapses, which have access to only local information about the state of the network, can still organize collectively and perform circuit-wide learning in an efficient manner. We show that such local learning actually optimizes a novel class of network-wide learning objectives. These objectives are based on similarities and contain a term that aligns the similarity of outputs to the similarity... Read more about C PEHLEVAN (Harvard)
  • 2019 Mar 28

    M PRIGOZHIN (Stanford)

    2:00pm to 3:00pm

    Location: 

    Maxwell-Dworkin, Rm 119, 33 Oxford St, Cambridge, MA 02138, USA

    "New Methods to Reveal the Nanoscale Motions of Macromolecules"

    Dr. Prigozhin develops new physical and molecular tools to “peer into the blind spots of cell signaling.” Max studied Chemistry & Physics at the University of Toronto before getting a PhD in Chemical Physics from UIUC. There he worked with Martin Gruebele, developing a multi-probe labeling strategy to reveal mechanisms of tertiary protein folding. He then moved to Steve Chu's lab at Stanford, where he has developed a new class of nanoparticle probes for multicolor biological electron microscopy. These...

    Read more about M PRIGOZHIN (Stanford)
  • 2019 Mar 28

    J LIPPINCOTT-SCHWARTZ (Janelia)

    12:00pm to 1:00pm

    Location: 

    Biological Laboratories (Biolabs) Room 1080, Divinity Avenue, Cambridge
    "Emerging imaging technologies to study cell architecture, dynamics and function"

    Powerful new ways to image the internal structures and complex dynamics of cells are revolutionizing cell biology and bio-medical research. In this talk, I will focus in particular on how emerging fluorescent technologies are increasing spatio-temporal resolution dramatically, permitting simultaneous multispectral imaging of multiple cellular components. Using these tools, it is now possible to begin constructing an “organelle interactome” describing the interrelationships of different... Read more about J LIPPINCOTT-SCHWARTZ (Janelia)
  • 2019 Jan 17

    QuantBio Seminar (QBS)

    5:00pm

    Location: 

    NorthWest Building, Room 425

    Mor Nitzan

    Charting a tissue from single-cell transcriptomes

     

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